Peyronie's Disease Treatment in Glendale, Arizona (AZ)

After your Peyronie’s disease diagnosis, your doctor may recommend waiting a year to see if the condition resolves itself non-surgically. If your doctor determines that more intervention is necessary, Peyronie’s disease may be treated with medication taken orally or injected into the penis. Your Urologist may consider surgical treatment options if time and medication prove ineffective. Because Peyronie’s disease is not fully understood, many treatments for the condition are considered experimental.

Nonsurgical Treatments for Peyronie's Disease

Medication for Peyronie’s disease can be administered orally or by injection.

Oral medications are still experimental in their use. Tamoxifen is an anti-estrogen, anti-inflammatory medication which researchers suggest may help reduce pain, plaque size, and penile curvature. Colchicine and carnitine are also anti-inflammatories which may have the ability to break apart hard plaque and thus alleviate symptoms. No placebo-controlled studies have been performed to determine the effectiveness of either Tamoxifen or Colchicine/carnitine.

Some smaller studies suggest that Vitamin E may reduce pain and penile curvature. Other smaller studies point to the usefulness of Potaba (potassium amino-benzoate) in reducing pain and penile plaque, but not penile curvature.

Injectable medication for Peyronie’s disease may allow higher doses to be administered with more local effects than oral medications. These may include Verapamil, a calcium channel blocker that is typically used in the treatment of high blood pressure. Verapamil disrupts collagen production and for this reason is used in the treatment of Peyrionie's disease. Several uncontrolled studies suggest that it reduced penile pain and curvature, but no large-scale placebo-controlled studies are available to confirm verapamil’s effectiveness.

In one large placebo controlled study, Interferon alpha-2b was injected directly into the scar tissue of the penis. Some men experienced relief from pain, penile curvature, and sexual function after receiving interferon injections. In one small study, men experienced some relief after receiving injections of the enzyme Collagenase into the penile plaque site. Researchers are looking forward to the results of a larger study currently underway.

Surgical Treatments for Peyronie's Disease

If time and medication are not effective in alleviating your symptoms, your doctor may recommend surgical options.

Grafting may effectively alleviate the symptoms of Peyronie’s by removing plaque on the penis and replacing it with healthy skin taken from another location on the body. Another surgical option for treating Peyronie’s disease is the Nesbit procedure in which the doctor slices the around the plaque, pulls the skin down to expose the underlying tissue, and then straitens the penis. Excess tissue is then removed or cinched together. Another procedure which may help treat Peyronie’s is implanting a prosthetic penile device to improve rigidity and straiten the penis.

Discuss treatment for Peyronie’s disease with your doctor to determine the best options for you.


About Yasmin Bootwala M.D.

Welcome and thank you for considering Arizona State Urology as your premiere center of urological care. 


Every patient in our practice is special and unique.  We will always strive to make sure that your visit with us is a personable and caring experience.  With your input and our access to the latest urological technologies, we will come up with a comprehensive treatment plan to address your every need.

Urology is the focus of study of the male and female urinary-tract system and male reproductive organs.  This deals with overactive bladders, UTI’s, cancers, and everything in between.  Having problems and needing to see a urologist is not as uncommon as some may think.

Since 1999, Arizona State Urology has been helping individuals with their urological needs in Arizona.  We have a team of top urologists that treat each individual person with the highest standards of care!  We treat men and women of any age to help with their needs.  At Arizona State Urology, you can expect to be treated not just as a patient, but as an individual with specific needs.  We are a top choice for a Urologist in Phoenix, Arizona!

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Phoenix, AZ 85016

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Featured Specialist for Peyronie's Disease Treatment in Glendale, AZ

Yasmin Bootwala M.D.

Arizona State Urology

Call Now: (602) 842-0469
6525 W Sack Dr Suite 201
Glendale, AZ 85308

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